Fioravanti, A., Antonelli, M., & Vitale, M. (2024). Advances in modern Balneology: new evidence-based indications from recent studies. International Journal of Biometeorology, 1-6. https://doi.org/10.1007/s00484-024-02749-8
By Dr. Michele Antonelli, MD - 10/04/2025
Balneotherapy, the therapeutic use of mineral-rich waters and muds, is experiencing a renaissance. Once associated only with rheumatic, respiratory or skin diseases, new research reveals it may offer real clinical benefits for a wide array of modern health challenges, including obesity, sleep disorders, mental health, Long-COVID, and even cancer rehabilitation.
While spa medicine has ancient roots, recent scientific efforts are bringing rigorous evidence into the picture. The World Health Organization already classifies balneotherapy as part of complementary medicine, and now modern studies are providing deeper insights into its mechanisms and medical relevance.
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"The Baths at Caracalla" (1899) by Lawrence Alma-Tadema
Recent evidence highlights new potential indications for balneotherapy:
Obesity and metabolic conditions: spa therapy, combined with diet and physical activity, may help reduce weight and manage type 2 diabetes or metabolic syndrome.
Sleep disorders: balneotherapy has been shown to improve perceived sleep quality, possibly due to thermoregulatory effects and decreased inflammatory markers.
Mental health: balneotherapy may reduce stress and anxiety through hormonal modulation involving cortisol and serotonin, offering a holistic support for mental wellness.
Long-COVID: spa facilities provide ideal environments for tailored rehabilitation protocols to address fatigue, muscle pain, and persistent respiratory problems.
Cancer recovery: though more studies are needed, preliminary findings suggest balneotherapy could ease fatigue, joint pain, and lymphedema in cancer survivors.
Researchers are also exploring the roles of thermal microbiota and hydrogen sulfide (H₂S), natural components of healing waters, in delivering anti-inflammatory and regenerative effects. Laboratory studies are unlocking the cellular mechanisms that may explain many of BT’s traditional claims.
In conclusion, balneotherapy is emerging not just as a relaxing retreat, but as an effective therapeutic option. As science continues to validate its benefits, it could play a more prominent role in public health and integrated medical care. While high-quality clinical trials are still needed, the future of balneology is brighter, and warmer, than ever.

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